6th Central - Eastern European congress
on cell free DNA and medical practice


7-8 March 2024, Olomouc, hotel Clarion




Kotva

FETMED (Centrum of fetal medicine, genetic and gynaecology) and SPADIA in cooperation with Society of Medical Genetics and Genomics, Olomouc, Czech Republic.


Under the auspices of:

prof. MUDr. Martin Procházka, Ph.D., Rector of Palacký University Olomouc
prof. MUDr. Tomáš Zima, DrSc., MBA, President-elect EFLM
prof.MUDr. Milan Macek, DrSc., Chairman of the Society of Medical Genetics and Genomics

Dear Friends and Colleagues

After very successful symposiums and conferences held in Budapest, Olomouc, Martin, Split and Debrecen we are delighted to invite you to join us in our beautiful city of Olomouc in the southeast part of Moravia in the Czech Republic to attend the  6th Central - Eastern European congress on cell free DNA and medical practice (CEE - cfDNA).

The aim of the meeting is to further deepen our knowledge of cfDNA and its fast-growing medical applications which are expanding beyond the Non-Invasive prenatal diagnosis. cfDNA in the blood and other body fluid testing is moving rapidly through development, implementation and towards global commercialization.

Our congress will help to disseminate knowledge among scientists, technicians and clinicians of Central – Eastern European countries and world-famous experts and researchers in the field while enabling to strengthen interpersonal links.

The symposium will define important areas of future research, such as methodological approaches to cfDNA detection, clinical applications and implementation and economical aspects.

We warmly invite you to make the most of this occasion to meet old friends, make new ones and, whatever stage you may be at in your career, to partake to the full in making this conference memorable by involving yourself in stimulating discussion and debate. And we wish you a wonderful pleasant stay in Olomouc.

 

On behalf of the whole team

  • Ishraq Dhaifalah
  • Martin Radina

 

The main aspects to be covered:

  1. cfDNA and applications in cancer
  2. cfDNA changing the face of prenatal care
  3. cfDNA a new era in the field of transplantation and autoimmune diseases
Miscellaneous- cfDNA and non-coding RNA in body fluids and neurology, cardiology, hearing and eye diseases



Kotva

Distinguished Invited Speakers

Professor Yuk-Ming Dennis Lo

Director of the Li Ka Shing Institute of Health Sciences,
Associate Dean (Research) of the Faculty of Medicine of CUHK.

Professor Kypros Nicolaides

The Director of the Harris Birthright Research King's College Hospital,
Founder and chairman of the of The Fetal Medicine Foundation (FMF) London, UK (FMF)

Professor Howard Cuckle DPhil

Emeritus Professor at the School of Medicine at the University of Leeds.

Peter Benn, BSc., MSc., PhD, DSc.

Emeritus Professor,
University of Connecticut Health Center,
Farmington, USA



International advisory committee

  • Howard Cuckle, UK
  • Peter Benn, USA
  • Balint Nagy, Hungary
  • Peter Celec, Slovakia
  • Zora Lasabová, Slovakia
  • Jasenka Wagner, Croatia
  • Tomáš Szemes, Slovakia
  • Gordan Lauc, Croatia
  • Ilona Hromadníková, Czechia
  • Hakan Savli, Turkey
  • Ripudaman Singh, Denmark


Scientific committee

  • Marek Godava
  • Radek Vodička
  • Josef Srovnal
  • Petr Džubák
  • Roman Hájek


Organization committee

  • Sandra Kubušková
  • Petra Rojíčková
  • Denisa Horáková
  • Barbora Němcová
  • Kateřina Vašková
  • Veronika Slavíková



Kotva

Abstracts

Abstract submission for CEEC cfDNA 2024 is close .


The final deadline for abstract submission is 15 February 2024, 23.59 hrs CET. Notifications about the outcome of the abstract assessment will be sent to all presenting authors in a timely manner.


Important Information on the Selection Process

All abstracts are reviewed by the Scientific Programme Committee. The best scored abstract in each category will be assigned to the according session. All other abstracts will be presented as posters in the poster area.
The format of acceptance will depend on the scoring result of the respective abstract.

 

IMPORTANT:

By submitting an abstract submitter agree that their personal data are being saved and used by the organiser in order to process the submission and enable the presentation at the conference.
You may be presenting author of only one paper, but co-author of any number of abstracts.
Identical submissions from different first authors will also be automatically rejected.

 

CEEC cfDNA Abstract Submission Topics 2024

  • Cell-free DNA in body fluids - origin, detection, etc.
  • Cell-free DNA in prenatal care, NIPT, perspective to future
  • Cell-free DNA and oncology – disease detection, monitoring, treatment,
  • Cell-free DNA autoimmune diseases and potentials in transplantation
  • cfDNA and non-coding RNA in body fluids and neurology, cardiology, hearing and eye diseases

 

Guidelines for submission

  • The abstract title must not be more than 25 words
  • Maximum number of words (exclusive title and names of authors): 300 words
  • Abstract needs to be structured accordingly: background, methods, results, conclusion
  • no tables/images allowed
  • abstracts need to be uploaded as Word (.docx, .doc) or Richt-Text (.rtf) file
  • authors: full name, institute and e-mail address of all authors: please mark the presenting author
  • Indicate title, name & affiliation of all co-authors


Kotva

Program

Thursday, March 7, 2024

12:00 – 18:00Registration
14:00 – 14:15

Opening:

I. Dhaifalah

Welcoming Address:

M. Procházka; T. Zima; M. Macek Jr.

14:15 – 14:30

Awards ceremony Chairs:

Assoc. Prof. I. Dhaifalah, Prof. M. Procházka, Prof. M. Macek Jr., Prof. M. Kacerovský


1) Golden Medal of the Palacký University in Olomouc

Awardee: Prof. Dennis Lo

2) Honorary Membership of the Czech Society of Medical Genetics & Genomics Awardees:

Prof. Peter Benn

Prof. Howard Cuckle

Prof. Dennis Lo

Prof. Kypros Nicolaides

3) Honorary Membership of the Czech Society of Perinatal Medicine

Awardee:

Prof. Dennis Lo

Prof. Kypros Nicolaides

4) Commemorative Mendel Coin Award of the Czech Society of Medical Genetics & Genomics

Awardee: Prof. Jiří Šantavý

 

cfDNA: Hope and potential applications in cancer I
Chairs: M. Minárik; J. Wagner; P. Celec.


14:30 – 14:50

Ondrej Pös, Jaroslav Budiš, Marcel Kucharík, et al.; Comenius Univ.,Bratislava, Slovakia

- Moving from NIPT to cancer screening: universality of low pass whole genome analysis

14:50 – 15:00

Beáta Soltész, Orsolya Biró, János Lukács, et al.; Univ. of Debrecen, Hungary

- Liquid biopsy, as the source of cell-free nucleic acid for the diagnosis, treatment, and monitoring of cancers

15:00 – 15:20

Marek Minárik; Charles Univ., & Elphogene, s.r.o., Prague, Czechia

- Application of oncoMonitor liquid biopsy assay for monitoring of therapy and minimal residual disease in various solid cancers

15:20 – 15:30

Abigél Balla, Péter Hunyadi, Szabolcs Máté, et al.; Semmelweis Univ.&Clinomics Europe Ltd., Budapest, Hungary

- Detection of homologous recombination deficiency using cell-free DNA whole-genome sequencing profile in ovarian cancer

15:30 – 15:50

Jasenka Wagner; J. J. Strossmayer Univ., Osijek, Croatia

- Analysis of miRNA in blood plasma-challenges and solutions

15:50 – 16:00

Gréta Gombos, András Penyige, Nikolett Németh, et al.; Univ. of Debrecen, Hungary

- Serous ovarian cancer microRNA profiling

16:00 – 16:20

COFFEE BREAK


cfDNA: Hope and potential applications in cancer II
Chairs: D. Lo; O. Biró, R.Hájek.


16:20 – 16:35

Dávid Kis, Péter Lukász, Anikó Serdült, et al. Clinomics Europe Ltd. Budapest, Hungary

- Preliminary European results on the clinical utility of ColonAiQ, a cell-free DNA methylation-based liquid biopsy assay for colorectal cancer early detection

16:35 – 16:50

Eva Szczyrbová, Hana Študentová, Jan Bouchal; Palacký Univ. Olomouc, Czechia

- Cell-free DNA for prostate cancer progression monitoring

16:50 – 17:05

Veronika Boušková, Lukáš Kobrle, Renata Koževnikovová, et al.; National Inst. of Public Health & Charles Univ., Czechia

- Characterization of small non-coding RNAs in plasma of breast carcinoma patients by next-generation sequencing

17:05 – 17:20

Nikolett Németh, Gréta Gombos, Andrea Bakó, et al.; Univ. of Debrecen, Hungary

- Mitochondrial DNA copy number as a minimally-invasive diagnostic biomarker of gliomas.

17:20 – 17:30

Jan Grohmann, Alexandra Kredatusova, Jana Navrátilová, et al.; Palacký Univ. and Univ. Hospital Olomouc, Czechia
- Detection of recurrent somatic variants in cell-free DNA as a tool for disease monitoring in Hodgkin lymphoma

17:30 – 17:40

Pavel Stejskal, Josef Srovnal, Monika Vidlařová, et al.; IMTM and Palacký Univ. Olomouc, Czechia

- Circulating tumor DNA-based analyses of solid tumors

17:40 – 18:00

Tomáš Zima and Drahomíra Springer; Charles Univ., Prague, Czechia

- Prenatal screening in Czech Republic: history, present, future

19:00 – 23:00

EVENING DINNER - hotel restaurant



Friday, March 8, 2024

cfDNA: Changing the face of prenatal care I
Chairs:M. Macek Sr., H. Cuckle, R. Singh


09:00 – 09:40

Prof. Dennis Lo; The Chinese Univ. of Hong Kong, China

Recent discoveries in the characteristics and clinical significance of cell-free DNA in plasma

09:40 – 10:00

Peter Benn; Univ. of Connecticut, USA

An overview of prenatal cf-DNA screening methods: clinical efficacy and scope

10:00 – 10:20

Howard Cuckle; Leeds, UK

Potential of cfDNA aneuploidy screening to reduce invasive prenatal testing

10:20 – 10:40

Martin Hynek; Charles Univ., Prague, Czechia

- What we know about cell free fetal DNA fragments

10:40 – 11:05

Ripudaman Singh; ARCEDI Biotech; Vejle, Denmark

- "Cell-based NIPT: Taking non-invasive screening beyond today's standards".

11:05 – 11:15

Dmytro Omelchenko, Dynex, Prague, Czechia
- Aviditysequencing: Novel technology thatexpandspossibilitiesof NGS applications

11:15 – 11:45

COFFEE BREAK

 

cfDNA: Changing the face of prenatal care II
Chairs: P. Benn, J. Šantavý, D. Stejskal


11:45 – 12:05

Kypros Nikolaides; Fetal Medicine Foundation, London, UK

cfDNA testing fortrisomies in the UK

12:05 – 12:25

Peter Benn; Univ. of Connecticut, USA

- Genome-wide non-invasive prenatal testing using cfDNA: the detection of rare autosomal trisomies

12:25 – 12:45

Howard Cuckle; Leeds, UK

- Review: cfDNA and cfRNA screening for preeclampsia and preterm birth

12:45 – 13:05

Ilona Hromadníková, Kateřina Kotlabová and Ladislav Krofta; Charles University, Prague, Czechia

- Novel early prediction modalities for pregnancy-related complications based on microRNA biomarkers and maternal clinical characteristics

13:05 – 13:20

Gabriel Minárik, Michaela Hýblova, Andrej Gnip and Dominik Hadzega; TrisomyTest Ltd., Bratislava, Slovakia

Pitfalls in the development and implementation of NIPT at the regional level: the Trisomy Test story

13:20 – 13:30

Tarja Ahola; Cuckle, Revvity / WallacOy, Turku, Finland

- Vanadis NIPT and beyond

13:30 – 14:30

LUNCH


cfDNA: Changing the face of prenatal care III
Chairs: T. Szemes; I. Hromadníková, M. Procházka


14:30 – 14:40

Marie Korabečná, Soňa Laššáková, Pavel Šenkyřík, et al.; Charles Univ., Prague, Czechia

- Rapid non-invasive prenatal screening test for trisomy 21 based on digital droplet PCR

14:40 – 14:50

Kristína Valovičová and Iveta Valášková; Masaryk Univ., Brno, Czechia

- Digital PCR in non-invasive prenatal testing

14:50 – 15:05

Martina Putzová, Paulasová Petra, Šprdlíková Lucie, et Bioptick á laboratory, Pilsen, Czechia
- Non-invasive prenatal screening for diagnostics for chromosomal abnormalities, and it´s relation to forensic practice

15:05 – 15:20

Martin Hynek; Charles University, Prague, Czechia

- Noninvasive prenatal tests of monogenic diseases: a current status.

15:20 – 15:35

David Stejskal, Smetanová Dagmar, Šimják Patriket, al.; Gennet Ltd., Prague, Czechia
- NIPT in a contingent screening protocol

15:35 – 15:45

Lenka Bich Nguyen Thi Ngoc, Jessica Sheardová, Pavlína Čadová, et al.; Gennet, Prague, Czechia
- "Cell-free DNA in the detection of chromosomal aneuploidies in early fetal demise and miscarriage

15:45 – 16:15

COFFEE BREAK


Application of cfDNA in other areas of medicine
Chairs: M. Korabečná, R. Vrtěl, M. Godava


16:15 – 16:30

Petra Hrubá Eva Girmanová, Petra Mrázová et al.; IKEM, Prague, Czechia

- dd-cf DNA as a tool to monitor antibody mediated rejection in kidney transplantation

16:30 – 16:55

Michal Pastorek, Bečka M., Borka G., et al.; Comenius Univ., Bratislava, Slovakia

- Pathological role of neutrophil extracellular traps-associated DNA in sterile inflammation

16:55 – 17:10

Paulína Belvončíková, Roman Gardlik, Barbora Gromová, et al.; Comenius Univ., Bratislava, Slovakia

- The dynamics of extracellular DNA and neutrophil extracellular traps formation in mouse models of chronic liver disease

17:10 – 17:25

Kristína Macáková, Veronika Borbélyová, B. M. Schuh , et Comenius Univ., Bratislava, Slovakia

- The role of extracellular DNA in pathogenesis of rheumatoid arthritis

17:25 – 17:35

Katarína Šebeková, Andrej Feješ, Veronika Kunšteková, et al.; Comenius Univ., Bratislava, Slovakia

- 6-month-long fast-food intake is associated with worse metabolic syndrome score and higher ecDNA levels in female rats

17:35 – 17:45

Ľubica Janovičová, Dominika Holániová, Barbora Vlková and Peter Celec; Comenius Univ., Bratislava, Slovakia

- Extracellular DNA in saliva is protected from cleavage by DNase I


Poster session


17:45 – 17:48

Radek Vrtěl, Jana Böhmová, Radek Vodička, et al.; Palacký Univ. Olomouc, Czechia

- Long experience and methodological progress of non-invasive cffDNA genotyping for assessment of clinically most significant maternal and fetal blood groups incompatibilities

17:48 – 17:51

Ivana Špálová and Marie Brejchová; Motol University Hosp., Prague, Czechia

- What do our medical students know about cell free DNA testing?

17:51 – 17:54

Barbora Belšánová, Kroupová P, Chmelářová A., et al.; Elphogene, s.r.o., Prague, Czechia

- Tight monitoring of ctDNA in patient undergoing multimodal treatment of metastatic colorectal cancer

17:54 – 17:57

Andrea Čeri, Marko Matusina; Marija Fabijanec, et al.; Univ. of Zagreb, Croatia

- Methodology challenges in isolation of circulating cell-free DNA from liquid biopsy samples in patients with colorectal adenoma



Kotva

Registration




Kotva

Sponsor and Exhibition possibilities

A sponsor opportunities are available for companies looking to meet new customers and reinforce existing relationships. An exhibition stand provides your company with real presence at the confrence and greatly facilitates networking.
It will be an intime meeting of experts with the purpose of exchanging knowledge and seeking new challenges and collaborations. We expect around 200 – 250 participants from about 20 different countries.


Sponsorship benefits and offers


If intrested Kindly contact the congress agency for more details.

Congress Business Travel, s.r.o., Lidická 43 / 66, 150 00 Praha 5
tel.: + 420 224 942 575, 224 942 579
e-mail: FETMED@cbttravel.cz
https://fetus.fetmed.cz/ceec-cfdna

 

Exhibition set up and dismantle

Address: Clarion Congress Hotel, Jeremenkova 36, 779 00 Olomouc

Marsh 7 th set-up: From…  am. Delegates registration opens at 8.00am.
Marsh 8th dismantle: From ….. until …..


Booth decorations
The price of the stand includes floor space, electricity, conference- charir(s) and table(s) and Wi-Fi. are any additional decoration materials and booth furniture should be granted by the eshibitors  themselves.

No items may be stapled, nailed, screwed, taped, etc, to the walls, floor or ceiling.
As a general rule, decorations, signs, and the like may only be placed on floor stands located a minimum of 20- 40 cm from the walls.




Kotva

General information

Venue and Location:
Clarion Congress Hotel, Jeremenkova 36, 779 00 Olomouc
www.clarioncongresshotelolomouc.com






Sponsors


Platinum partner





Gold partner





Silver partner





Partners









Kotva

Contact

FETUS
cesta životem



Zina Pecková

E fetmed@cbttravel.cz
T +420 606 918 277, +420 224 942 575, +420 224 942 579

Congress Business Travel
Lidická 43 / 66, 150 00 Praha 5