FETUS
cesta životem
Professor Yuk-Ming Dennis Lo
Director of the Li Ka Shing Institute of Health Sciences,
Associate Dean (Research) of the Faculty of Medicine of CUHK.
6th Central - Eastern European congress
on cell free DNA and medical practice
7-8 March 2024, Olomouc, hotel Clarion
FETMED (Centrum of fetal medicine, genetic and gynaecology) and SPADIA in cooperation with Society of Medical Genetics and Genomics, Olomouc, Czech Republic.
prof. MUDr. Martin Procházka, Ph.D., Rector of Palacký University Olomouc
prof. MUDr. Tomáš Zima, DrSc., MBA, President-elect EFLM
prof.MUDr. Milan Macek, DrSc., Chairman of the Society of Medical Genetics and Genomics
After very successful symposiums and conferences held in Budapest, Olomouc, Martin, Split and Debrecen we are delighted to invite you to join us in our beautiful city of Olomouc in the southeast part of Moravia in the Czech Republic to attend the 6th Central - Eastern European congress on cell free DNA and medical practice (CEE - cfDNA).
The aim of the meeting is to further deepen our knowledge of cfDNA and its fast-growing medical applications which are expanding beyond the Non-Invasive prenatal diagnosis. cfDNA in the blood and other body fluid testing is moving rapidly through development, implementation and towards global commercialization.
Our congress will help to disseminate knowledge among scientists, technicians and clinicians of Central – Eastern European countries and world-famous experts and researchers in the field while enabling to strengthen interpersonal links.
The symposium will define important areas of future research, such as methodological approaches to cfDNA detection, clinical applications and implementation and economical aspects.
We warmly invite you to make the most of this occasion to meet old friends, make new ones and, whatever stage you may be at in your career, to partake to the full in making this conference memorable by involving yourself in stimulating discussion and debate. And we wish you a wonderful pleasant stay in Olomouc.
On behalf of the whole team
The main aspects to be covered:
Professor Yuk-Ming Dennis Lo
Director of the Li Ka Shing Institute of Health Sciences,
Associate Dean (Research) of the Faculty of Medicine of CUHK.
Professor Kypros Nicolaides
The Director of the Harris Birthright Research King's College Hospital,
Founder and chairman of the of The Fetal Medicine Foundation (FMF) London, UK (FMF)
Professor Howard Cuckle DPhil
Emeritus Professor at the School of Medicine at the University of Leeds.
Peter Benn, BSc., MSc., PhD, DSc.
Emeritus Professor,
University of Connecticut Health Center,
Farmington, USA
The final deadline for abstract submission is 15 February 2024, 23.59 hrs CET. Notifications about the outcome of the abstract assessment will be sent to all presenting authors in a timely manner.
Important Information on the Selection Process
All abstracts are reviewed by the Scientific Programme Committee. The best scored abstract in each category will be assigned to the according session. All other abstracts will be presented as posters in the poster area.
The format of acceptance will depend on the scoring result of the respective abstract.
IMPORTANT:
By submitting an abstract submitter agree that their personal data are being saved and used by the organiser in order to process the submission and enable the presentation at the conference.
You may be presenting author of only one paper, but co-author of any number of abstracts.
Identical submissions from different first authors will also be automatically rejected.
CEEC cfDNA Abstract Submission Topics 2024
Guidelines for submission
| 12:00 – 18:00 | Registration |
| 14:00 – 14:15 | Opening: I. Dhaifalah Welcoming Address: M. Procházka; T. Zima; M. Macek Jr. |
| 14:15 – 14:30 | Awards ceremony Chairs: Assoc. Prof. I. Dhaifalah, Prof. M. Procházka, Prof. M. Macek Jr., Prof. M. Kacerovský 1) Golden Medal of the Palacký University in Olomouc Awardee: Prof. Dennis Lo 2) Honorary Mendel Medal Award & The Honorary Membership of the Czech Society of Medical Genetics & Genomics Prof. Peter Benn Prof. Howard Cuckle Prof. Dennis Lo Prof. Kypros Nicolaides 3) Honorary Membership of the Czech Society of Perinatal Medicine Awardee: Prof. Dennis Lo Prof. Kypros Nicolaides 4) Commemorative Mendel Coin Award of the Czech Society of Medical Genetics & Genomics Awardee: Prof. Jiří Šantavý |
cfDNA: Hope and potential applications in cancer I
Chairs: M. Minárik; J. Wagner; P. Celec.
| 14:30 – 14:50 | Ondrej Pös, Jaroslav Budiš, Marcel Kucharík, et al.; Comenius Univ.,Bratislava, Slovakia - Moving from NIPT to cancer screening: universality of low pass whole genome analysis |
| 14:50 – 15:00 | Beáta Soltész, Orsolya Biró, János Lukács, et al.; Univ. of Debrecen, Hungary - Liquid biopsy, as the source of cell-free nucleic acid for the diagnosis, treatment, and monitoring of cancers |
| 15:00 – 15:20 | Marek Minárik; Charles Univ., & Elphogene, s.r.o., Prague, Czechia - Application of oncoMonitor liquid biopsy assay for monitoring of therapy and minimal residual disease in various solid cancers |
| 15:20 – 15:30 | Abigél Balla, Péter Hunyadi, Szabolcs Máté, et al.; Semmelweis Univ.&Clinomics Europe Ltd., Budapest, Hungary - Detection of homologous recombination deficiency using cell-free DNA whole-genome sequencing profile in ovarian cancer |
| 15:30 – 15:50 | Jasenka Wagner; J. J. Strossmayer Univ., Osijek, Croatia - Analysis of miRNA in blood plasma-challenges and solutions |
| 15:50 – 16:00 | Gréta Gombos, András Penyige, Nikolett Németh, et al.; Univ. of Debrecen, Hungary - Serous ovarian cancer microRNA profiling |
| 16:00 – 16:20 | COFFEE BREAK |
cfDNA: Hope and potential applications in cancer II
Chairs: D. Lo; O. Biró, R.Hájek.
| 16:20 – 16:35 | Dávid Kis, Péter Lukász, Anikó Serdült, et al. Clinomics Europe Ltd. Budapest, Hungary - Preliminary European results on the clinical utility of ColonAiQ, a cell-free DNA methylation-based liquid biopsy assay for colorectal cancer early detection |
| 16:35 – 16:50 | Eva Szczyrbová, Hana Študentová, Jan Bouchal; Palacký Univ. Olomouc, Czechia - Cell-free DNA for prostate cancer progression monitoring |
| 16:50 – 17:05 | Veronika Boušková, Lukáš Kobrle, Renata Koževnikovová, et al.; National Inst. of Public Health & Charles Univ., Czechia - Characterization of small non-coding RNAs in plasma of breast carcinoma patients by next-generation sequencing |
| 17:05 – 17:20 | Nikolett Németh, Gréta Gombos, Andrea Bakó, et al.; Univ. of Debrecen, Hungary - Mitochondrial DNA copy number as a minimally-invasive diagnostic biomarker of gliomas. |
| 17:20 – 17:30 | Jan Grohmann, Alexandra Kredatusova, Jana Navrátilová, et al.; Palacký Univ. and Univ. Hospital Olomouc, Czechia |
| 17:30 – 17:40 | Pavel Stejskal, Josef Srovnal, Monika Vidlařová, et al.; IMTM and Palacký Univ. Olomouc, Czechia - Circulating tumor DNA-based analyses of solid tumors |
| 17:40 – 18:00 | Tomáš Zima and Drahomíra Springer; Charles Univ., Prague, Czechia - Prenatal screening in Czech Republic: history, present, future |
| 19:00 – 23:00 | EVENING DINNER - hotel restaurant |
cfDNA: Changing the face of prenatal care I
Chairs:M. Macek Sr., H. Cuckle, R. Singh
| 09:00 – 09:40 | Prof. Dennis Lo; The Chinese Univ. of Hong Kong, China - Recent discoveries in the characteristics and clinical significance of cell-free DNA in plasma |
| 09:40 – 10:00 | Peter Benn; Univ. of Connecticut, USA - An overview of prenatal cf-DNA screening methods: clinical efficacy and scope |
| 10:00 – 10:20 | Howard Cuckle; Leeds, UK - Potential of cfDNA aneuploidy screening to reduce invasive prenatal testing |
| 10:20 – 10:40 | Martin Hynek; Charles Univ., Prague, Czechia - What we know about cell free fetal DNA fragments |
| 10:40 – 11:05 | Ripudaman Singh; ARCEDI Biotech; Vejle, Denmark - Positioning, Performance and Relevance of Cell-based Non-invasive Prenatal Testing |
| 11:05 – 11:15 | Dmytro Omelchenko, Dynex, Prague, Czechia |
| 11:15 – 11:45 | COFFEE BREAK |
cfDNA: Changing the face of prenatal care II
Chairs: P. Benn, J. Šantavý, D. Stejskal
| 11:45 – 12:05 | Kypros Nikolaides; Fetal Medicine Foundation, London, UK (Virtually) - cfDNA testing fortrisomies in the UK |
| 12:05 – 12:25 | Peter Benn; Univ. of Connecticut, USA - Genome-wide non-invasive prenatal testing using cfDNA: the detection of rare autosomal trisomies |
| 12:25 – 12:45 | Howard Cuckle; Leeds, UK - Review: cfDNA and cfRNA screening for preeclampsia and preterm birth |
| 12:45 – 13:05 | Ilona Hromadníková, Kateřina Kotlabová and Ladislav Krofta; Charles University, Prague, Czechia - Novel early prediction modalities for pregnancy-related complications based on microRNA biomarkers and maternal clinical characteristics |
| 13:05 – 13:20 | Gabriel Minárik, Michaela Hýblova, Andrej Gnip and Dominik Hadzega; TrisomyTest Ltd., Bratislava, Slovakia - Pitfalls in the development and implementation of NIPT at the regional level: the Trisomy Test story |
| 13:20 – 13:30 | Tarja Ahola; Howard Cuckle, Revvity / WallacOy, Turku, Finland - Vanadis NIPT and beyond |
| 13:30 – 14:30 | LUNCH |
cfDNA: Changing the face of prenatal care III
Chairs: T. Szemes; I. Hromadníková, M. Procházka
| 14:30 – 14:40 | Marie Korabečná, Soňa Laššáková, Pavel Šenkyřík, et al.; Charles Univ., Prague, Czechia - Rapid non-invasive prenatal screening test for trisomy 21 based on digital droplet PCR |
| 14:40 – 14:50 | Kristína Valovičová and Iveta Valášková; Masaryk Univ., Brno, Czechia - Digital PCR in non-invasive prenatal testing |
| 14:50 – 15:05 | Martina Putzová, Paulasová Petra, Šprdlíková Lucie, et Bioptick á laboratory, Pilsen, Czechia |
| 15:05 – 15:20 | Martin Hynek; Cell-based NIPT: Taking non-invasive screening beyond today's standard, Charles University, Prague, Czechia - Noninvasive prenatal tests of monogenic diseases: a current status. |
| 15:20 – 15:35 | David Stejskal, Smetanová Dagmar, Šimják Patriket, al.; Gennet Ltd., Prague, Czechia |
| 15:35 – 15:45 | Lenka Bich Nguyen Thi Ngoc, Jessica Sheardová, Pavlína Čadová, et al.; Gennet, Prague, Czechia |
| 15:45 – 16:15 | COFFEE BREAK |
Application of cfDNA in other areas of medicine
Chairs: M. Korabečná, R. Vrtěl, M. Godava
| 16:15 – 16:30 | Petra Hrubá Eva Girmanová, Petra Mrázová et al.; IKEM, Prague, Czechia - dd-cf DNA as a tool to monitor antibody mediated rejection in kidney transplantation |
| 16:30 – 16:55 | Michal Pastorek, Bečka M., Borka G., et al.; Comenius Univ., Bratislava, Slovakia - Pathological role of neutrophil extracellular traps-associated DNA in sterile inflammation |
| 16:55 – 17:10 | Paulína Belvončíková, Roman Gardlik, Barbora Gromová, et al.; Comenius Univ., Bratislava, Slovakia - The dynamics of extracellular DNA and neutrophil extracellular traps formation in mouse models of chronic liver disease |
| 17:10 – 17:25 | Kristína Macáková, Veronika Borbélyová, B. M. Schuh , et Comenius Univ., Bratislava, Slovakia - The role of extracellular DNA in pathogenesis of rheumatoid arthritis |
| 17:25 – 17:35 | Katarína Šebeková, Andrej Feješ, Veronika Kunšteková, et al.; Comenius Univ., Bratislava, Slovakia - 6-month-long fast-food intake is associated with worse metabolic syndrome score and higher ecDNA levels in female rats |
| 17:35 – 17:45 | Ľubica Janovičová, Dominika Holániová, Barbora Vlková and Peter Celec; Comenius Univ., Bratislava, Slovakia - Extracellular DNA in saliva is protected from cleavage by DNase I |
Poster session
| 17:45 – 17:48 | Radek Vrtěl, Jana Böhmová, Radek Vodička, et al.; Palacký Univ. Olomouc, Czechia - Long experience and methodological progress of non-invasive cffDNA genotyping for assessment of clinically most significant maternal and fetal blood groups incompatibilities |
| 17:48 – 17:51 | Ivana Špálová and Marie Brejchová; Motol University Hosp., Prague, Czechia - What do our medical students know about cell free DNA testing? |
| 17:51 – 17:54 | Barbora Belšánová, Kroupová P, Chmelářová A., et al.; Elphogene, s.r.o., Prague, Czechia - Tight monitoring of ctDNA in patient undergoing multimodal treatment of metastatic colorectal cancer |
| 17:54 – 17:57 | Andrea Čeri, Marko Matusina; Marija Fabijanec, et al.; Univ. of Zagreb, Croatia - Methodology challenges in isolation of circulating cell-free DNA from liquid biopsy samples in patients with colorectal adenoma |
A sponsor opportunities are available for companies looking to meet new customers and reinforce existing relationships. An exhibition stand provides your company with real presence at the confrence and greatly facilitates networking.
It will be an intime meeting of experts with the purpose of exchanging knowledge and seeking new challenges and collaborations. We expect around 200 – 250 participants from about 20 different countries.
Sponsorship benefits and offers
If intrested Kindly contact the congress agency for more details.
Congress Business Travel, s.r.o., Lidická 43 / 66, 150 00 Praha 5
tel.: + 420 224 942 575, 224 942 579
e-mail: FETMED@cbttravel.cz
https://fetus.fetmed.cz/ceec-cfdna
Exhibition set up and dismantle
Address: Clarion Congress Hotel, Jeremenkova 36, 779 00 Olomouc
Marsh 7 th set-up: From… am. Delegates registration opens at 8.00am.
Marsh 8th dismantle: From ….. until …..
Booth decorations
The price of the stand includes floor space, electricity, conference- charir(s) and table(s) and Wi-Fi. are any additional decoration materials and booth furniture should be granted by the eshibitors themselves.
No items may be stapled, nailed, screwed, taped, etc, to the walls, floor or ceiling.
As a general rule, decorations, signs, and the like may only be placed on floor stands located a minimum of 20- 40 cm from the walls.
Venue and Location:
Clarion Congress Hotel, Jeremenkova 36, 779 00 Olomouc
www.clarioncongresshotelolomouc.com
Zina Pecková
E fetmed@cbttravel.cz
T +420 606 918 277, +420 224 942 575, +420 224 942 579
Congress Business Travel
Lidická 43 / 66, 150 00 Praha 5
FETUS
cesta životem
Horní Lán 1312/12a, 7790 00 Olomouc, Czech Republic | T +420 605 825 780 | E asistent@fetmed.cz | www.fetmed.cz
Fotogalerie
